Inside every cell, NAD⁺ powers the processes that keep you alive.
Inside every cell
NAD⁺ is present in all your cells.
It’s the universal cofactor that lets energy and repair systems switch on exactly when needed.
Transfers energy
NAD⁺ shuttles power from food, becoming NADH and driving ATP production in the mitochondria.
That same flow also fuels key enzymes that keep cellular programs calibrated.
Keeps cells strong
Healthy NAD⁺ levels mean steady energy, faster repair, and better redox balance.
Cells stay resilient - supporting clear thinking, endurance, and healthier aging.
Benefits
DNA repair
Scientific:
NAD⁺ acts as a critical substrate for PARP (poly ADP-ribose polymerase) enzymes that detect and repair DNA strand breaks. Maintaining adequate NAD⁺ levels supports genomic stability, counteracting the cumulative DNA damage associated with aging and environmental stress.
Layman’s:
NAD⁺ helps your cells repair damaged DNA - like a built-in maintenance system that keeps your body’s blueprint strong and youthful.
Energy metabolism
Scientific:
NAD⁺ is essential in redox reactions that drive cellular respiration, transferring electrons in glycolysis and the mitochondrial electron transport chain. It underpins ATP production, making it fundamental for energy metabolism.
Layman’s:
Your cells use NAD⁺ to turn food into energy. Higher NAD⁺ levels mean your body can produce energy more efficiently, helping you feel more alert and active.
Sirtuin activation
Scientific:
Sirtuins (SIRT1–7) are NAD⁺-dependent deacetylases that regulate gene expression, stress resistance, and longevity pathways. NAD⁺ availability directly controls sirtuin activity, influencing metabolic health and cellular resilience.
Layman’s:
NAD⁺ switches on “longevity enzymes” called sirtuins that help protect your cells, regulate metabolism, and slow down aspects of the aging process.
Cell signaling
Scientific: NAD⁺ serves as a signaling molecule influencing calcium signaling, immune response, and intracellular communication. Its metabolites (e.g., cyclic ADP-ribose) play key roles in regulating cellular communication and stress responses.
Layman’s: NAD⁺ helps your cells talk to each other properly, ensuring they respond to stress and stay in sync for healthy body function.
Mitochondrial function
Scientific:
As a cofactor in mitochondrial oxidative phosphorylation, NAD⁺ regulates energy transfer and mitochondrial biogenesis. Elevated NAD⁺ supports efficient ATP production and reduces mitochondrial dysfunction, a hallmark of aging.
Layman’s:
NAD⁺ keeps your cell’s “power plants” (mitochondria) running smoothly, so your body can produce clean, steady energy without fatigue.
Redox balance
Scientific:
NAD⁺/NADH ratios maintain cellular redox balance, modulating oxidative stress and metabolic pathways. This balance prevents excess free radical formation and supports cellular homeostasis.
Layman’s:
NAD⁺ helps your body control oxidation - the process that causes stress and damage in cells - keeping your system in balance and reducing inflammation.
Healthy aging
Scientific:
By sustaining DNA repair, mitochondrial function, and sirtuin activity, NAD⁺ counters molecular damage accumulation, improving cellular resilience and promoting healthspan rather than just lifespan.
Layman’s:
Rising NAD⁺ levels help your body age more gracefully - supporting energy, cell health, and vitality as the years go by.
Cognitive function
Scientific:
NAD⁺ enhances neuronal metabolism, supports mitochondrial energy supply in neurons, and modulates neuroprotective sirtuin pathways (notably SIRT1 and SIRT3), mitigating cognitive decline linked to NAD⁺ depletion.
Layman’s:
NAD⁺ fuels your brain cells, supporting focus, memory, and mental clarity while protecting against age-related cognitive slowdown.
Immune support
Scientific:
NAD⁺ regulates immune cell metabolism and inflammatory signaling through CD38 and SIRT1 pathways. Restoring NAD⁺ improves immune surveillance and reduces chronic inflammation (“inflammaging”).
Layman’s:
NAD⁺ helps your immune system work efficiently - defending against illness while preventing the overactive inflammation linked to aging.
Metabolic health
Scientific:
NAD⁺ modulates insulin sensitivity, lipid oxidation, and glucose metabolism through sirtuin and AMPK activation. Its decline is associated with obesity, insulin resistance, and metabolic syndrome.
Layman’s:
NAD⁺ supports a healthy metabolism - helping your body process sugar and fat more effectively and maintain balanced energy levels.
Recovery & performance
Scientific:
NAD⁺ replenishment enhances mitochondrial efficiency, reduces oxidative stress, and improves cellular recovery following exertion or injury by supporting ATP regeneration and inflammation control.
Layman’s:
By boosting cellular energy and repair, NAD⁺ helps your body recover faster from workouts, stress, or fatigue - improving endurance and performance.
Feel the difference
in just days.
“NAD⁺ is the closest we’ve gotten to a fountain of youth… without it, you’re dead in 30 seconds.”
- David Sinclair, Harvard Genetics Professor
⚡️ Energy that lasts 12+ hours
🧠 Sharper focus & mental clarity
🔄 Faster recovery & reduced fatigue
Users report more productive mornings, improved mood, and deeper physical and mental stamina - without stimulants or crashes.
Absorption matters.
Not all NAD⁺ is created equal.
Oral capsules often break down in digestion. The nasal spray absorbs directly through the nasal mucosa - bypassing the gut for fast, effective delivery.
Trusted by those who perform at the highest level.
From athletes to entrepreneurs and Hollywood icons, NAD+ has become the quiet edge they rely on to stay sharp, recover faster, and push the limits of their performance both mentally and physically.
For so long, NAD+ was locked behind £1,000+ IV sessions at private clinics. Now, only DIYNAD+ brings you the purest, cleanest version - made simple and affordable, from just £3.93 per day.
Clinic results.
Without the clinic cost.
As Bryan Johnson explained in his Diary of a CEO interview, NAD⁺ IV drips only provide short-lived benefits - you’d need to go back regularly to sustain results. That means constant clinic visits and thousands spent on treatments, which makes it impractical for most people. The DIYNAD+ Nasal Spray was designed to solve this problem: same active compound, but affordable, consistent, and convenient to use at home.
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