Scientific:
NAD⁺ acts as a critical substrate for PARP (poly ADP-ribose polymerase) enzymes that detect and repair DNA strand breaks. Maintaining adequate NAD⁺ levels supports genomic stability, counteracting the cumulative DNA damage associated with aging and environmental stress.
Layman’s:
NAD⁺ helps your cells repair damaged DNA - like a built-in maintenance system that keeps your body’s blueprint strong and youthful.

Scientific:
NAD⁺ is essential in redox reactions that drive cellular respiration, transferring electrons in glycolysis and the mitochondrial electron transport chain. It underpins ATP production, making it fundamental for energy metabolism.
Layman’s:
Your cells use NAD⁺ to turn food into energy. Higher NAD⁺ levels mean your body can produce energy more efficiently, helping you feel more alert and active.

Scientific:
Sirtuins (SIRT1–7) are NAD⁺-dependent deacetylases that regulate gene expression, stress resistance, and longevity pathways. NAD⁺ availability directly controls sirtuin activity, influencing metabolic health and cellular resilience.
Layman’s:
NAD⁺ switches on “longevity enzymes” called sirtuins that help protect your cells, regulate metabolism, and slow down aspects of the aging process.

Scientific: NAD⁺ serves as a signaling molecule influencing calcium signaling, immune response, and intracellular communication. Its metabolites (e.g., cyclic ADP-ribose) play key roles in regulating cellular communication and stress responses.

Layman’s: NAD⁺ helps your cells talk to each other properly, ensuring they respond to stress and stay in sync for healthy body function.

Scientific:
As a cofactor in mitochondrial oxidative phosphorylation, NAD⁺ regulates energy transfer and mitochondrial biogenesis. Elevated NAD⁺ supports efficient ATP production and reduces mitochondrial dysfunction, a hallmark of aging.
Layman’s:
NAD⁺ keeps your cell’s “power plants” (mitochondria) running smoothly, so your body can produce clean, steady energy without fatigue.

Scientific:
NAD⁺/NADH ratios maintain cellular redox balance, modulating oxidative stress and metabolic pathways. This balance prevents excess free radical formation and supports cellular homeostasis.
Layman’s:
NAD⁺ helps your body control oxidation - the process that causes stress and damage in cells - keeping your system in balance and reducing inflammation.

Scientific:
By sustaining DNA repair, mitochondrial function, and sirtuin activity, NAD⁺ counters molecular damage accumulation, improving cellular resilience and promoting healthspan rather than just lifespan.
Layman’s:
Rising NAD⁺ levels help your body age more gracefully - supporting energy, cell health, and vitality as the years go by.

Scientific:
NAD⁺ enhances neuronal metabolism, supports mitochondrial energy supply in neurons, and modulates neuroprotective sirtuin pathways (notably SIRT1 and SIRT3), mitigating cognitive decline linked to NAD⁺ depletion.
Layman’s:
NAD⁺ fuels your brain cells, supporting focus, memory, and mental clarity while protecting against age-related cognitive slowdown.

Scientific:
NAD⁺ regulates immune cell metabolism and inflammatory signaling through CD38 and SIRT1 pathways. Restoring NAD⁺ improves immune surveillance and reduces chronic inflammation (“inflammaging”).
Layman’s:
NAD⁺ helps your immune system work efficiently - defending against illness while preventing the overactive inflammation linked to aging.

Scientific:
NAD⁺ modulates insulin sensitivity, lipid oxidation, and glucose metabolism through sirtuin and AMPK activation. Its decline is associated with obesity, insulin resistance, and metabolic syndrome.
Layman’s:
NAD⁺ supports a healthy metabolism - helping your body process sugar and fat more effectively and maintain balanced energy levels.

Scientific:
NAD⁺ replenishment enhances mitochondrial efficiency, reduces oxidative stress, and improves cellular recovery following exertion or injury by supporting ATP regeneration and inflammation control.
Layman’s:
By boosting cellular energy and repair, NAD⁺ helps your body recover faster from workouts, stress, or fatigue - improving endurance and performance.

Yes. The DIYNAD+ Pen is manufactured in a sterile, medical-grade facility and designed for safe, subcutaneous self-administration. Each pen is pre-filled with pharmaceutical-grade NAD+ solution and individually sealed. When used according to our step-by-step guide, the process is clean, controlled, and safe.

Most users describe it as a mild pinch. The ultra-fine needle is much smaller than a typical syringe, making the process nearly painless compared to traditional injections.

For optimal cellular energy and recovery, we recommend one injection every 2 days. However, dosage frequency can vary based on your goals - some customers use it daily during periods of fatigue, jet lag, or recovery.

Absolutely. You can manage, pause, or cancel your subscription at any time from your account dashboard. There are no hidden fees or lock-ins - you’re in full control.

Anyone who is pregnant, breastfeeding, under 18, or has a serious medical condition should consult a healthcare professional before use. If you have known allergies to NAD⁺ ingredients or experience any unusual symptoms, discontinue use immediately and seek medical advice.

Many customers report increased energy, sharper focus, and improved mood within the first few doses. For deeper cellular repair and recovery benefits, consistent use over several weeks delivers the best results.

Store your pen in a cool, dry place away from direct sunlight. Always replace the cap securely after each use and keep it out of reach of children.

The most common and comfortable areas are the abdomen or outer thigh - areas with a small layer of fat beneath the skin. Rotate sites with each use to avoid irritation. A full step-by-step guide is included with your order and available on our website.

Yes, you can travel with your pen. Keep it in its original packaging and store it in your carry-on luggage.

Side effects are rare and typically mild if they occur - because NAD⁺ is a naturally occurring molecule in the body, adverse reactions are uncommon.